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FOXO3A (phospho-S253) Rabbit Monoclonal Antibody -BS9944M

FOXO3A (phospho-S253) Rabbit Monoclonal Antibody -BS9944M

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FOXO3A (phospho-S253) Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS9944M-50, BS9944M-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O43524

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:1000-1:5000
IHC: 1:50-1:200

Background: FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Forkhead transcription factors of the FoxO subfamily are emerging as a shared component among pathways regulating diverse cellular functions, such as differentiation, metabolism, proliferation, and survival. Their transcriptional output is controlled via a two-tiered mechanism of phosphorylation and acetylation.FOXO3A is a transcriptional activator which triggers apoptosis in the absence of survival factors.

Purification and Purity: Protein A affinity purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of FOXO3A protein only when phosphorylated at Ser253.

Bioworld Molecular Weight: ~ 71, 97 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of FOXO3A (phospho-S253) Rabbit mAb at 1:1000 dilution
Lane 1: Hela whole cell lysate
Lane 2: PC12 whole cell lysate, Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Phospho-FOXO3A (S253) antibody. Counter stained with hematoxylin.

Alternative Name: Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3; FKHRL1; FOXO3A

Immunogen: Recombinant antibody.

Conjugate: Unconjugated

Modification: Phosphorylation