FOXO3A Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90530-50, BS90530-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: O43524(Human) Q9WVH4(Mouse)
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB, ICC IHC FC
All Applications: WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Purification and Purity: Peptide affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: FOXO3A polyclonal antibody detects endogenous levels of FOXO3A protein.
Bioworld Molecular Weight: 71 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of FOXO3A on different cell lysate using anti-FOXO3A antibody at 1/500 dilution.
Positive control:
Lane 1: SH-SY5Y
Lane 2: K562, ICC staining FOXO3A in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: FOXO3, FKHRL1, FOXO3A, AF6q21, AF6q21 protein, DKFZp781A0677, FKHR2, FKHRL 1, FKHRL1, FKHRL1P2, Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1, Forkhead box O3, Forkhead box O3A, Forkhead box protein O3, Forkhead box protein O3A, Forkhead Drosophila homolog of in rhabdomyosarcoma like 1, Forkhead homolog (rhabdomyosarcoma) like 1, Forkhead in rhabdomyosarcoma like 1, Forkhead in rhabdomyosarcoma-like 1, FOX O3A, FOXO2, foxo3, FOXO3, FOXO3A, MGC12739, MGC31925,
Immunogen: Peptide
Conjugate: Unconjugated
Modification: Unmodified