FoxO4 (Acetyl Lys189) rabbit pAb - ES8622

FoxO4 (Acetyl Lys189) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8622-50, ES8622-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],

Alternate Name: Forkhead box protein O4 (Fork head domain transcription factor AFX1)

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000, ELISA 1:10000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthetic Acetyl peptide from human protein at AA range: 189

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 55kD

Human Gene ID: 4303

Human SWISS Prot NO: P98177

Subcellular Location: Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.

Research Use Only