Product Description

FoxO4 (phospho-S197) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS4714-50, BS4714-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: FOX4 is a forkhead transcription factor involved in the regμlation of the insμlin signaling pathway. It binds to insμlin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regμlates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modμlated genes. It is also involved in negative regμlation of the cell cycle.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Forkhead box protein O4, Fork head domain transcription factor AFX1, AFX, AFX1, MLLT7, FOXO4

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic phosphopeptide derived from human FoxO4 around the phosphorylation site of Serine 197.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: p-FoxO4 (S197) polyclonal antibody detects endogenous levels of FoxO4 protein only when phosphorylated at Ser197.

Molecular Weight: ~ 55, 70 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P98177

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only