Product Description

FoxO4 (phospho-T451) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS4687-50, BS4687-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: FOX4 is a forkhead transcription factor involved in the regμlation of the insμlin signaling pathway. It binds to insμlin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regμlates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modμlated genes. It is also involved in negative regμlation of the cell cycle.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: Forkhead box protein O4, Fork head domain transcription factor AFX1, AFX, AFX1, MLLT7, FOXO4

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic phosphopeptide derived from human FoxO4 around the phosphorylation site of Threonine 451.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: p-FoxO4 (T451) polyclonal antibody detects endogenous levels of FoxO4 protein only when phosphorylated at Thr198.

Molecular Weight: ~ 70 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P98177

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only