Product Description

FOXO4 Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16717-50, BZ16717-100

Swiss-Prot: P98177

Host: Rabbit

FOXO4 Polyclonal Antibody-BZ16717

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IP, , FC

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background: The Forkhead family of transcription factors is involved in tumorigenesis of rhabdomyosarcoma and acute leukemias. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 54 kDa; Observed MW: 65 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FoxO4 in Human heartLysates using FOXO4 antibody., Immunofluorescence analysis of FOXO4 in Hela using FoxO4 antibody.

Alternative Name: FOXO4; AFX; AFX1; MLLT7; Forkhead box protein O4; Fork head domain transcription factor AFX1

Immunogen: A synthesized peptide derived from human FoxO4

Modification: Unmodified

Conjugate: Unconjugated