FoxP2 Monoclonal Antibody
Size: 50μL, 100μL
Catalogue Numbers: RA11240-50, RA11240-100
Citations, Manuals and MSDS Available upon request.
Background: forkhead box P2 (FOXP2) Homo sapiens This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isofor
Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.
Storage Instructions: -20°C/1 year
Applications: WB; ELISA
Species Cross-Reactivity: Human
GeneID (Human): 93986
SWISS: O15409
Source: Mouse
Research Use Only