Product Description

FOXP3 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16033-50, BZ16033-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q9BZS1

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 47 kDa; Observed MW: 47 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FOXP3 in PC-12 lysates using FOXP3 antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsilla using FOXP3 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunohistochemistry analysis of paraffin-embedded Human bladder cancer using FOXP3 antibody. High-pressure and temperature Tris-EDTA was used for antigen retrieval., Immunohistochemistry analysis of paraffin-embedded Human colon using FOXP3 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: FOXP3; IPEX; JM2; Forkhead box protein P3; Scurfin

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human FOXP3. AA range:381-430

Conjugate: Unconjugated

Modification: Unmodified