FPGS Monoclonal Antibody-MB10936

FPGS Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10936-50, MB10936-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q05932

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,

All Applications: WB: 1/500-1/1000

Background: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Unsubstituted reduced folates are the preferred substrates. Metabolizes methotrexate (MTX) to polyglutamates.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 65 kDa; Observed MW: 65 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FPGS in rat lung lysates using FPGS antibody., Western blot analysis of FPGS in K562, 3T3 lysates using FPGS antibody.

Alternative Name: FPGS; Tetrahydrofolate synthase

Immunogen: A synthetic peptide of human FPGS

Conjugate: Unconjugated

Modification: Unmodified