Product Description

FPRL1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS66133-50, BS66133-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: FPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerfμl neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R coμld resμlt in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granμlocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: ALXR, FMLP R I, FMLP R II, FMLP related receptor I, FMLP-R-I, FMLP-R-II, FMLP-related receptor I, FMLPX, Formyl peptide receptor 2, Formyl peptide receptor like 1, Formyl peptide receptor related, Formyl peptide receptor-like 1, FPR 2, FPR2, FPR2_HUMAN, FPR2A, FPRH 1, FPRH 2, FPRH1, FPRH2, FPRL 1, FPRL1, HM63, Lipoxin A4 receptor, LXA4 receptor, LXA4R, N-formyl peptide receptor 2, RFP

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human FPRL1: 51-150/351

Dilution: WB: 1:500-1:2000
ELISA: 1:5000-1:10000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: FPRL1 Polyclonal Antibody detects endogenous levels of FPRL1 protein.

Molecular Weight: ~ 48 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P25090

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only