FREM1 Polyclonal Antibody - E-AB-66871

FREM1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-66871-60, E-AB-66871-120, E-AB-66871-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: FREM1

Target Synonym: FREM1; BNAR; C9orf143; C9orf145; C9orf154; MOTA; TILRR; TRIGNO2

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q5H8C1

Background: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human FREM1 (NP_659403.4).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 25kDa/42kDa/80kDa/244kDa

Observed MW: 72kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only