Frizzled-2 rabbit pAb - ES5417

Frizzled-2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5417-50, ES5417-100

Citations, Manuals and MSDS Available upon request.

Background: frizzled class receptor 2 (FZD2) Homo sapiens This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010],

Alternate Name: FZD2; Frizzled-2; Fz-2; hFz2; FzE2

Source: Rabbit

Applications: WB; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human FZD2. AA range:201-250

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 55kD

Human Gene ID: 2535

Human SWISS Prot NO: Q14332

Subcellular Location: Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Research Use Only