Frizzled-7 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA20683-50, RA20683-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: frizzled class receptor 7 (FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008], Reactivity: Human, Mouse Host: Rabbit Applications: WB, IF/ICC, ELISA Alternate Names: FZD7, Frizzled-7, Fz-7, hFz7, FzE3 Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. Molecular Weight: 64 Protein Molecular Weight (kDa): 64 Storage: -20°C/1 year Human Gene ID: 8324 Human SwissProt Number: O75084 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only