Product Description

FRMPD2 Polyclonal Antibody

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65443-50, BS65443-100

Swiss-Prot: Q68DX3

Host: Rabbit

FRMPD2 Polyclonal Antibody-BS65443

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,

Applications: IHC-P

All Applications: IHC-P=1:100-500

Background: This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants.

Purification and Purity: affinity purified by Protein A

Specificity: FRMPD2 Polyclonal Antibody detects endogenous levels of FRMPD2 protein.

Bioworld Molecular Weight: 144kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Paraformaldehyde-fixed, paraffin embedded (mouse brain)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FRMPD2) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C., Paraformaldehyde-fixed, paraffin embedded (rat brain)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FRMPD2) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C.

Alternative Name: FERM and PDZ domain containing protein 2; PDZ domain containing protein 4; PDZ domain containing protein 5C; PDZ domain containing 4 PDZD5C; PDZK4; PDZK5C; FRPD2_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from human PDZK4:1001-1100/1309

Modification: Unmodified

Conjugate: Unconjugated