FRZB Polyclonal Antibody-BS8276

FRZB Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8276-50, BS8276-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q92765

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB IF

All Applications: WB: 1:500~1:2000
IF: 1:50~1:200

Background: The frizzled gene, originally identified in Drosophila melanogaster, was shown to be involved in the development of tissue polarity. The mammalian homolog of frizzled as well as several secreted mammalian frizzled-related proteins, FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The Frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif, and they function as receptors for Wnt. The Frizzled-1 gene maps to human chromosome 7q21 and is expressed in adult heart, placenta, lung, kidney, pancreas, prostate and ovary and in fetal lung and kidney. Frizzled-2 is expressed in adult heart and fetal brain, lung and kidney.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FRZB polyclonal antibody detects endogenous levels of FRZB protein.

Bioworld Molecular Weight: ~ 36 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot (WB) analysis of FRZB polyclonal antibody

Alternative Name: Secreted frizzled-related protein 3; sFRP-3; Frezzled; Fritz; Frizzled-related protein 1; FrzB-1; FRZB; FIZ; FRE; FRP; FRZB1; SFRP3

Immunogen: Recombinant full length Human FRZB.

Conjugate: Unconjugated

Modification: Unmodified