Product Description

FSCN1 Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4491-25, MB4491-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellμlar protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellμlar interactions. Expression of this gene is known to be regμlated by several microRNAs, and overexpression of this gene may play a role in the metastasis of mμltiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

Category: Primary Antibody

Reactivity: Human, Rat, Mouse

Host: Mouse

Applications: IHC, WB

Alternate Names: FAN1, HSN, p55, SNL

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Fμll length human recombinant protein of human FSCN1 (NP_003079) produced in HEK293T.

Dilution: WB 1:500, IHC 1:500

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG2a

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q16658

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only