FTO Polyclonal Antibody - E-AB-68312

FTO Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-68312-60, E-AB-68312-120, E-AB-68312-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: FTO

Target Synonym: FTO; ALKBH9; BMIQ14; GDFD

Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9C0B1

Background: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human FTO

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 6kDa/12kDa/14kDa/58kDa

Observed MW: 60KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only