Product Description

FucT-IV (E71) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3444-50, BS3444-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: FucT-IV (α 1, 3-fucosyltransferase IV), also known as FUT4, FCT3A or ELFT, is a 405 amino acid single-pass type II membrane protein that localizes to Golgi stacks. During embryogenesis, FucT-IV is highly expressed in skin, liver, kidney, muscle and small intestine where it functions to catalyze the glycosidic attachment of α-fucose to various molecμles, such as N-acetyllactosamines. Via its catalytic activity, FucT-IV participates in the synthesis of carbohydrate molecμles like the cell-adhesion antigen CD15 (also known as Lewis X), thereby playing a roll in cell cycle events such as apoptosis and cellcell binding. Overexpression of FucT-IV is implicated in epithelial cancers, suggesting a possible role for FucT-IV in carcinogenesis.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Alpha-(1, 3)-fucosyltransferase 4, ELAM-1 ligand fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Fuc-TIV, FucT-IV, Galactoside 3-L-fucosyltransferase, FUT4, ELFT, FCT3A

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 45-90 of Human FucT-IV.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: FucT-IV (E71) polyclonal antibody detects endogenous levels of FucT-IV protein.

Molecular Weight: ~ 72 kDa

Pathway: Tumor-Infiltrating Immune Cell Marker Guide, ESC Pluripotency and Differentiation Signaling Pathway,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P22083

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only