Product Description

FUK (Q26) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2330-50, BS2330-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Blood group antigen recognition, metastasis and inflammation utilize fucose, a sugar found in glycoproteins and glycolipids. Fucokinase, also designated L-fucose kinase or FUK, is a 1, 084 amino acid enzyme that plays a role in the salvage pathway of fucose reutilization. A member of the GHMP kinase family, Fucokinase exists as two alternative splice variants and catalyzes L-fucose phosphorylation to form β-L-fucose 1-phosphate. The gene encoding Fucokinase maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn’s disease, which is a gastrointestinal inflammatory condition.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: L-fucose kinase, Fucokinase, FUK

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 10-70 of Human Fucokinase.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Fucokinase (Q26) polyclonal antibody detects endogenous levels of Fucokinase protein.

Molecular Weight: ~ 118 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8N0W3

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only