Product Description

FURIN Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32385-50, RA32385-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: furin, paired basic amino acid cleaving enzyme (FURIN) Homo sapiens This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. The product of this gene is one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix m

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 87

Protein Molecular Weight (kDa): 87

Storage: -20°C/1 year

Human Gene ID: 5045

Human SwissProt Number: P09958

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only