Product Description

Fusion glycoProtein F0 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90543-50, BS90543-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: W8CLH7

Host: Rabbit

Reactivity: Avian avulavirus 1

Applications: WB, ELISA

All Applications: WB:1:500-1,000
ELISA:1:5,000-1:10,000

Background: During virus entry, induces fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2. Interacts directly with heparan sulfate and may participate in virus attachment. Furthermore, the F2 subunit was identifed as the major determinant of RSV host cell specificity. Later in infection, proteins F expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis. The fusion protein is also able to trigger p53-dependent apoptosis.

Purification and Purity: Peptide affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Fusion glycoprotein F0 on Fusion glycoprotein F0 transfected HEK293 cellLysates using anti- Fusion glycoprotein F0 antibody at 1/500 dilution.

Bioworld Molecular Weight: 59 kDa

Specificity: Fusion glycoprotein F0 polyclonal antibody detects endogenous levels of Fusion glycoprotein F0 protein.

Alternative Name: F, F, Fusion glycoprotein F0, Protein F, RSV Fusion (F) Glycoprotein,

Immunogen: Peptide

Conjugate: Unconjugated

Modification: Unmodified