FYB Polyclonal Antibody-BS62547

FYB Polyclonal Antibody

Catalogue Numbers: BS62547-50, BS62547-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O15117

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB:1:500~1:1000

Background: Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FYB polyclonal antibody detects endogenous levels of FYB protein.

Extra Notes: Western blot (WB) analysis of FYB polyclonal antibody at 1:500 dilution
LaneA:H9C2 whole cell lysate
LaneB:SP2/0 whole cell lysate
LaneC:PC3 whole cell lysate

Bioworld Molecular Weight: ~ 110 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: ADAP; p120/p130; FYB1; FYB; SLAP130; Adhesion and degranulation promoting adaptor protein;; Fyb; FYB-120/130; FYN binding protein; FYN-binding protein; FYN-T-binding protein; SLAP-130; SLAP130; SLP-76-associated phosphoprotein

Immunogen: Synthetic peptide, corresponding to Human FYB.

Conjugate: Unconjugated

Modification: Unmodified