Product Description

FYN (4B8) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3021-50, MB3021-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P06241

Host: Mouse

Reactivity: Human, Monkey, Rat, Mouse,

Applications: WB, ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG2b

Bioworld Molecular Weight: Calculated MW: 61 kDa; Observed MW: 61 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Fyn in Hela, 3T3, C6, COS7, CEM, Ramos and Jurkat lysates using Fyn antibody., Immunocytochemistry analysis of FYN in HeLa using Fyn antibody.

Alternative Name: FYN; Tyrosine-protein kinase Fyn; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-Fyn

Immunogen: Purified recombinant human Fyn protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified