Product Description

FYN Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10946-50, MB10946-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P39688

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,

All Applications: WB: 1/500-1/1000

Background: Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 61 kDa; Observed MW: 61 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Fyn in U87-MG, 3T3 muscle lysates using FYN antibody., Western blot analysis of Fyn in rat Brain lysates using Fyn antibody.

Alternative Name: AI448320; AW552119

Immunogen: A synthetic peptide of mouse Fyn

Conjugate: Unconjugated

Modification: Unmodified