Gα t2 rabbit pAb - ES5568

Gα t2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5568-50, ES5568-100

Citations, Manuals and MSDS Available upon request.

Background: Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. [provided by RefSeq, Jul 2008],

Alternate Name: GNAT2; GNATC; Guanine nucleotide-binding protein G (t) subunit alpha-2; Transducin alpha-2 chain

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human GNAT2. AA range:1-50

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 40kD

Human Gene ID: 2780

Human SWISS Prot NO: P19087

Subcellular Location: Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment. Localizes mainly in the outer segment in the dark-adapted state, whereas is translocated to the inner part of the photoreceptors in the light-adapted state. During dark-adapted conditions, in the presence of UNC119 mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light.

Research Use Only