G3BP-1 (D226) Polyclonal Antibody-BS1132

G3BP-1 (D226) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS1132-50, BS1132-100

Sizes: 50µl, 100µl

Swiss-Prot: Q13283

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC

Background: G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: G3BP-1 (D226) polyclonal antibody detects endogenous levels of G3BP-1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of G3BP-1 (D226) polyclonal antibody at 1:500 dilution
Lane 1: A549 cell lysate
Lane 2: Mouse heart tissue lysate
Lane 3: Rat heart tissue lysate, Immunohistochemistry (IHC) analyzes of G3BP-1 (D226) pAb in paraffin-embedded human lymphoma tissue.

Bioworld Molecular Weight: ~ 52 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: G3BP1; G3BP; hDH VIII; G3BP-1; Ras GTPase-activating protein-binding protein 1; GAP SH3 domain-binding protein 1

Immunogen: Synthetic peptide, corresponding to amino acids 196-246 of Human G3BP-1.

Conjugate: Unconjugated

Modification: Unmodified