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G3BP1 Polyclonal Antibody-BS8472

G3BP1 Polyclonal Antibody-BS8472

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G3BP1 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS8472-50, BS8472-100

Swiss-Prot: Q13283

Host: Rabbit

G3BP1 Polyclonal Antibody-BS8472

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Duck

Applications: WB, IF

All Applications: WB: 1:500~1:2000
IF: 1:50~1:200

Background: G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: G3BP1 polyclonal antibody detects endogenous levels of G3BP1 protein.

Bioworld Molecular Weight: ~ 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using G3BP1 antibody., Immunofluorescence analysis of U20S cell using G3BP1 antibody. Blue: DAPI for nuclear staining.

Alternative Name: G3BP1; G3BP; hDH VIII; G3BP-1; Ras GTPase-activating protein-binding protein 1; GAP SH3 domain-binding protein 1

Immunogen: Recombinant full length Human G3BP1.

Modification: Unmodified

Conjugate: Unconjugated

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