Product Description

G6PC2 Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02763-20, BT-AP02763-50, BT-AP02763-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate| the terminal step in gluconeogenic and glycogenolytic pathways| allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity| but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined.

Research Areas: Immunology; Metabolism; Signal transduction

Target Protein: G6PC2

Applications: WB

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: G6PC2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9NQR9; Mouse: Q9Z186

Synonyms: G6PC2; Glucose-6-phosphatase 2; G-6-Pase 2; G6Pase 2; EC 3.1.3.9; Islet-specific glucose-6-phosphatase catalytic subunit-related protein

GeneID: Human: 57818; Mouse: 14378

Research Use Only