G6PD Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90547-50, BS90547-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P11413(Human)
Host: Rabbit
Reactivity: Human
Applications: WB, ICC IHC FC
All Applications: WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background: Glucose-6-phosphate 1-dehydrogenase (G6PD) plays an important role in the pentose phosphate pathway. It is a member of the glucose-6-phosphate dehydrogenase family of proteins. G6PD is a ubiquitous enzyme that produces pentose sugars for nucleic acid synthesis, but is also involved in carbohydrate degradation, as it is one of the main producers of NADPH reducing power. G6PD has NADP as a co-factor and structural element. It can be found as a homodimer or homotetramer, and is primarily detected in lymphoblasts, granulocytes and sperm. Defects in G6PD can cause chronic non-spherocytic hemolytic anemia (CNSHA), especially in areas in which malaria is an epidemic. Individuals with a high level of G6PD-deficiency are at higher risk of acute hemolytic attacks.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: G6PD polyclonal antibody detects endogenous levels of G6PD protein.
Bioworld Molecular Weight: 59 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Glucose 6 Phosphate Dehydrogenase on A549 cell lysate using anti-Glucose 6 Phosphate Dehydrogenase antibody at 1/1,000 dilution., ICC staining Glucose 6 Phosphate Dehydrogenase in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: G6PD, G6PD, G6PD, G6PD1, G6pdx, Glucose 6 phosphate 1 dehydrogenase, Glucose 6 phosphate dehydrogenase, Glucose 6 phosphate dehydrogenase, G6PD, Glucose-6-phosphate 1-dehydrogenase, MET19, POS10, Zwf1p,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified