Product Description

GABA A Receptor α4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25169-50, RA25169-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: gamma-aminobutyric acid type A receptor alpha4 subunit (GABRA4) Homo sapiens Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section)

Alternate Names: GABRA4, Gamma-aminobutyric acid receptor subunit alpha-4, GABA (A) receptor subunit alpha-4

Clonality: Polyclonal

Dilution: WB 1:1000-2000, IHC 1:100-200

Molecular Weight: 62

Protein Molecular Weight (kDa): 62

Storage: -20°C/1 year

Human Gene ID: 2557

Human SwissProt Number: P48169

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only