GABA A Receptor α4 Polyclonal Antibody - RA25169

GABA A Receptor α4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25169-50, RA25169-100

Citations, Manuals and MSDS Available upon request.

Background: gamma-aminobutyric acid type A receptor alpha4 subunit (GABRA4) Homo sapiens Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1) . Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000, IHC 1:100-200

Alternative Names: GABRA4; Gamma-aminobutyric acid receptor subunit alpha-4; GABA (A) receptor subunit alpha-4

Applications: WB; IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 2557

Protein MW (KDa): 62

SWISS: P48169

Source: Rabbit

Research Use Only