Product Description

GABA B Receptor 2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65739-50, BS65739-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimμlates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modμlates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regμlating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit

Host: Rabbit

Applications: WB

Alternate Names: GABBR2, GB2, G protein coupled receptor 51, G-protein coupled receptor 51, GAB B R2, GABA B R2, GABA B receptor 2, GABA B RECEPTOR, GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABA[[B]]R2, GABAB R2, GABABR 2, GABABR2, GABB R2, GABBR 2, Gabbr2, GABR2_HUMAN, Gamma aminobutyric acid (GABA) B receptor 2, Gamma aminobutyric acid B receptor 2, Gamma aminobutyric acid GABA B receptor 2, Gamma aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid type B receptor subunit 2, Gb 2, Gb2, GH07312, GPR 51, GPR51, GPRC 3B, GPRC3B, HG 20, HG20, HRIHFB2099, Metabotropic GABA B receptor subtype 2, OTTHUMP00000021776, OTTHUMP00000063797, R2 SUBUNIT, BcDNA:GH07312, CG6706, CT20836, D GABA[[B]]R2, D Gaba2, FLJ36928, GABR2_HUMAN.  

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human GABABR2:501-650/941

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: GABA B Receptor 2 Polyclonal Antibody detects endogenous levels of GABA B Receptor 2 protein.

Molecular Weight: 125 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O75899

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only