GABAA Rα1 (L361) Polyclonal Antibody-BS3563

GABAA Rα1 (L361) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3563-50, BS3563-100

Sizes: 50µl, 100µl

Swiss-Prot: P14867

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

Background: GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA Rγ1-3, GABAA Rδ, GABAA Rε, GABAA Rρ1 and GABAA Rρ2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: GABAA Rα1 (L361) polyclonal antibody detects endogenous levels of GABAA Rα1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of GABAA Rα1 (L361) pAb in paraffin-embedded human brain tissue.

Bioworld Molecular Weight: ~ 52 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Gamma-aminobutyric acid receptor subunit alpha-1; GABa (A) receptor subunit alpha-1; GABRA1; GABAARα1

Immunogen: Synthetic peptide, corresponding to amino acids 330-380 of Human GABAA Rα1.

Conjugate: Unconjugated

Modification: Unmodified