Product Description

GABAA Rα1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25176-50, RA25176-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: gamma-aminobutyric acid type A receptor alpha1 subunit (GABRA1) Homo sapiens This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC-p, IF (paraffin section), WB, ELISA

Alternate Names: GABRA1, Gamma-aminobutyric acid receptor subunit alpha-1, GABA (A) receptor subunit alpha-1

Clonality: Polyclonal

Dilution: WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight: 51

Protein Molecular Weight (kDa): 51

Storage: -20°C/1 year

Human Gene ID: 2554

Human SwissProt Number: P14867

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only