GABAA Rβ1 (phospho Ser434) rabbit pAb - ES1452

GABAA Rβ1 (phospho Ser434) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1452-50, ES1452-100

Citations, Manuals and MSDS Available upon request.

Background: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008],

Alternate Name: GABRB1; Gamma-aminobutyric acid receptor subunit beta-1; GABA (A) receptor subunit beta-1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human GABA-RB around the phosphorylation site of Ser434. AA range:401-450

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 55kD

Human Gene ID: 2560

Human SWISS Prot NO: P18505

Subcellular Location: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Research Use Only