GABAA Rα1 Polyclonal Antibody - RA25176

GABAA Rα1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25176-50, RA25176-100

Citations, Manuals and MSDS Available upon request.

Background: gamma-aminobutyric acid type A receptor alpha1 subunit (GABRA1) Homo sapiens This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: GABRA1; Gamma-aminobutyric acid receptor subunit alpha-1; GABA (A) receptor subunit alpha-1

Applications: IHC-p; IF (paraffin section) ; WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 2554

Protein MW (KDa): 51

SWISS: P14867

Source: Rabbit

Research Use Only