Product Description

GABARAPL2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-62383-60, E-AB-62383-120, E-AB-62383-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GABARAPL2

Target Synonym: GABARAPL2; ATG8; ATG8C; GATE-16; GATE16; GEF-2; GEF2

Research Areas: Cancer,Metabolism,Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P60520

Background: Ubiquitin-like modifier involved in intra-Golgi traffic (By similarity. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation (By similarity. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human GABARAPL2

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW: 13kDa

Observed MW: 14kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only