GADD34 rabbit pAb - ES8613

GADD34 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8613-50, ES8613-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008],

Alternate Name: Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog)

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000, ELISA 1:10000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthetic peptide from human protein at AA range: 430-490

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 73kD

Human Gene ID: 23645

Human SWISS Prot NO: O75807

Subcellular Location: Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Associates with membranes via an N-terminal amphipathic intramembrane region.

Research Use Only