GALC Polyclonal Antibody - E-AB-62750

GALC Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-62750-60, E-AB-62750-120, E-AB-62750-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GALC

Target Synonym: GALC

Research Areas: Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P54803

Background: This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human GALC (NP_000144.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:100

Calculated MW: 67kDa/74kDa/77kDa

Observed MW: 77kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only