Product Description

Galectin-3 (N174) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1137-50, BS1137-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicμlar carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregμlated expression of galectin-3 is involved in cancer progression and metastasis. galectin-3 mediates the endocytosis of β-1 Integrins in a lactose-dependant manner and is associated with thyroid malignancy and Crohn’s disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: CBP35, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3, MAC2, Galectin 3, Galectin3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Synthetic peptide, corresponding to amino acids 140-190 of Human Galectin-3.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Galectin-3 (N174) polyclonal antibody detects endogenous levels of Galectin-3 protein.

Molecular Weight: ~ 30 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P17931

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only