Product Description

Galectin-9 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS48254-50, BS48254-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Binds galactosides (By similarity). Has high affinity for the Forssman pentasaccharide (By similarity). Ligand for HAVCR2/TIM3 (By similarity). Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (By similarity). Also stimμlates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellμlar bacterial growth (PubMed:20937702). Ligand for P4HB, the interaction retains P4HB at the cell surface of Th2 T-helper cells, increasing disμlfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration (PubMed:21670307). Ligand for CD44, the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regμlation of FOXP3 expression and increased induced regμlatory T (iTreg) cell stability and suppressive function (PubMed:25065622).

Category: Primary Antibody

Reactivity: Mouse

Host: Rabbit

Applications: WB

Alternate Names: gal-9, Lgals5, LGALS35, AA407335, AI194909, AI265545, galectin-9

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of mouse Galectin-9

Dilution: WB: 1:1000

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 40 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O08573

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only