Product Description

GAlpha i-3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03867-20, BT-AP03867-50, BT-AP03867-100

Citations, Manuals and MSDS Available upon request.

Background: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. GNAI3 encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.

Research Areas: Signal Transduction

Target Protein: GNAI3

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Galpha i-3 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 40532

UniProt Accession: Human: P08754; Mouse: Q9DC51; Rat: P08753

Synonyms: GNAI3; Guanine nucleotide-binding protein G(k) subunit alpha; G(i) alpha-3

GeneID: Human: 2773; Mouse: 14679; Rat: 25643

Research Use Only