GANP Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA25214-50, RA25214-100
Citations, Manuals and MSDS Available upon request.
Background: minichromosome maintenance complex component 3 associated protein (MCM3AP) Homo sapiens The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. [provided by RefSeq, Jan 2014],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Alternative Names: MCM3AP; GANP; KIAA0572; MAP80; 80 kDa MCM3-associated protein; Protein GANP
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 8888
Protein MW (KDa): 218
SWISS: O60318
Source: Rabbit
Research Use Only