Product Description

GAP43 (A35) Polyclonal Antibody

Catalogue Numbers: BS3655-50, BS3655-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P17677

Host: Rabbit

Reactivity: Rat, Mouse

Applications: WB

All Applications: WB: 1:2000~1:5000

Background: GAP-43 (growth associated protein 43, B-50, PP46, calmodulin-binding protein P-57, neuromodulin, neuron growth-associated protein 43, protein F1 is a crucial component for regenerative response in the nervous system. It is present at high levels in neuronal growth cones during development and axonal regeneration. GAP-43 is normally produced by neurons during developmental growth and axonal regeneration, but it is also expressed in specific regions of the normal adult nervous system. The neuron-specific Elav/Hu family member, HuD, interacts with and stabilizes GAP-43 mRNA in developing neurons and leads to increased levels of GAP-43 protein.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GAP43 (A35) polyclonal antibody detects endogenous levels of GAP43 protein.

Extra Notes: Western blot (WB) analysis of GAP43 (A35) polyclonal antibody at 1:2000 dilution
Lane1:The Brain tissue lysate of Rat(40ug)
Lane2:The Brain tissue lysate of Mouse(40ug)

Bioworld Molecular Weight: ~ 43 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Neuromodulin; Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50; pp46; GAP43

Immunogen: Synthetic peptide, corresponding to Human GAP43.

Conjugate: Unconjugated

Modification: Unmodified