GAS2 rabbit pAb - ES9683

GAS2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES9683-50, ES9683-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2009],

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 34kD

Human Gene ID: 2620

Human SWISS Prot NO: O43903

Subcellular Location: Cytoplasm, cytoskeleton, stress fiber. Membrane; Peripheral membrane protein. Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles.

Research Use Only