Product Description

GATA6 Monoclonal Antibody

Catalogue Numbers: MB66495-50, MB66495-100

Sizes: 50µl, 100µl

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q92908

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: GATA proteins comprise a group of transcription factors that are related by the presence of conserved zinc finger DNA-binding domains, which bind directly to the nucleotide sequence core element GATA . There are six vertebrate GATA proteins, designated GATA-1 to GATA-6 .
GATA-6 plays a critical role in endoderm development . It is essential for development of the heart, gut, and other organs . Knock out of GATA-6 is embryonic lethal due to defects in formation of the heart tube and a failure to develop extraembryonic endoderm . Loss of expression, or loss of nuclear localization of GATA-6 is apparent in a large number of ovarian tumors .

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of GATA6 protein.

Extra Notes: Western blot analysis of GATA6 expression in Hela (A), Hela (B), 293T (C) whole cell lysates.

Bioworld Molecular Weight: ~ 60 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Transcription factor GATA-6; GATA-binding factor 6

Immunogen: Purified recombinant human GATA6 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified