Product Description

GBA Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66790-50, MB66790-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: b-glucosidase is a predominantly liver enzyme which efficiently hydrolyzes b-D-glucoside and b-D-galactoside. Defects in b-glucosidase cause Gaucher disease, an inherited condition distinguished by the accumμlation of glucosylceramide within the cells of the reticμloendothelial system. b-glucosidase is used in enzyme replacement treatment aimed at treating Gaucher disease. The absorption of dietary flavonoid glycosides in humans involves a critical deglycosylation step that is mediated by epithelial b-glucosidases.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: GC, GLUC, Glucosylceramidase, Acid beta-glucosidase, Alglucerase, Beta-glucocerebrosidase, Beta-GC, D-glucosyl-N-acylsphingosine glucohydrolase, Imiglucerase

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GBA. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Specificity: Recognizes endogenous levels of GBA protein.

Molecular Weight: ~ 57 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P04062

Product: Mouse IgM. Supplied in crude ascites with 0.01% sodium azide.

Research Use Only