GBA Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90565-50, BS90565-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P04062(Human) EntrezGene:684536 (Rat)
Host: Rabbit
Reactivity: Human, Rat
Applications: WB, IHC
All Applications: WB:1:1,000-1:5,000
IHC:1:50-1:200
Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: GBA polyclonal antibody detects endogenous levels of GBA protein.
Bioworld Molecular Weight: 60 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of GBA on diffewrent cells lysates using anti-GBA antibody at 1/1,000 dilution.
Positive control:
Lane 1: HepG2
Lane 2: 293T, Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-GBA antibody. Counter stained with hematoxylin.
Alternative Name: Beta-GC, GBA, Acid beta glucosidase, Acid beta-glucosidase, Alglucerase, Beta glucocerebrosidase, BETA GLUCOSIDASE, ACID, Beta-glucocerebrosidase, betaGC, D glucosyl N acylsphingosine glucohydrolase, D-glucosyl-N-acylsphingosine glucohydrolase, EC 3.2.1.45, GBA, Gba protein, GBA1, GC, GCase, GCB, GLCM, GLUC, Glucocerebrosidase (alt.), Glucocerebrosidase, GLUCOCEREBROSIDASE PSEUDOGENE, Glucosidase beta, Glucosidase, beta, acid, Glucosidase, beta; acid (includes glucosylceramidase), Glucosylceramidase, Imiglucerase, Lysosomal glucocerebrosidase, OTTHUMP00000033992, OTTHUMP00000033993,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified