GBDR1 rabbit pAb - ES2405

GBDR1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2405-50, ES2405-100

Citations, Manuals and MSDS Available upon request.

Background: function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 STI1 domain., similarity:Contains 1 ubiquitin-like domain., similarity:Contains 2 UBA domains., subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain., tissue specificity:Ubiquitous.,

Alternate Name: UBAC1; GBDR1; KPC2; UBADC1; Ubiquitin-associated domain-containing protein 1; UBA domain-containing protein 1; E3 ubiquitin-protein ligase subunit KPC2; Glialblastoma cell differentiation-related protein 1; Kip1 ubiquitination-promoting com

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human UBAC1. AA range:91-140

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 45kD

Human Gene ID: 10422

Human SWISS Prot NO: Q9BSL1

Subcellular Location: Cytoplasm

Research Use Only