GBRD Polyclonal Antibody-BS65284

GBRD Polyclonal Antibody

Catalogue Numbers: BS65284-50, BS65284-100

Sizes: 50µl, 100µl

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: O14764

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,IHC-p,IF(paraffin section),ELISA

All Applications: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Background: gamma-aminobutyric acid type A receptor delta subunit(GABRD) Homo sapiens Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GABAA Rδ Polyclonal Antibody detects endogenous levels of GABAA Rδ protein.

Extra Notes: Western blot analysis of lysates from LOVO and HT-29 cells, using GABRD Antibody. The lane on the right is blocked with the synthesized peptide.

Bioworld Molecular Weight: ~ 51 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: GABRD; Gamma-aminobutyric acid receptor subunit delta; GABA(A) receptor subunit delta

Immunogen: The antiserum was produced against synthesized peptide derived from human GABRD. AA range:141-190

Conjugate: Unconjugated

Modification: Unmodified